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doi: 10.1016/j.chom.2020.01.028

Furthermore, mitochondrial membrane potential was significantly increased in both cell lines following 24 h treatment with 10 mM metformin, when compared to control ( Figure 1E )

No other issues were flagged, according to Alvotech

Inhibition of CDK11 for 30 min fully abrogated the phosphorylation of SF3B1 as well as phosphorylation of Thr806 in SPT5, a recently identified CDK11 substrate 74

Reduces joint stiffness and friction, moisturizes skin, and relieves dryness and itching caused by arthritis