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Simultaneously, catalytically produced hydrogen peroxide (H 2 O 2 ) activates the protein transient receptor potential melastatin 2 (TRPM2) ion channel, promotes calcium influx, activates macrophages, and induces systemic immune response (Fig

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The beads settled faster than and hence separated from the unbound cells easily

The pretreatment of BMDCs with dead cells led to TGF- and IL-10 production through MerTK, and a reduction in IFN- levels, suggesting that dead cells induced by VSV infection induce innate anergy and limit the antiviral immune response [44]