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Importance of Glutathione
Across the cagrilintide clinical program, the dominant tolerability issues have been gastrointestinal: nausea, reduced appetite, constipation, and, less commonly, vomiting a profile shared with pramlintide and with GLP-1 agonists, and mechanistically expected from a compound that slows the stomach and engages the area postrema
Gallbladder complications and acute pancreatitis remain rare but documented risks requiring baseline screening, especially for those planning significant dietary changes
The company forecasts mid- to high-single digit percentage net sales growth in 2025
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