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Other participating personnel, including patients, outcome assessors and persons performing the data analysis, will remain blinded from the time of randomization to the time of database unlock

Bone Density: Studies (Johansen et al.) show it increases Longitudinal Bone Growth Rate (LGR) and bone mineral content by stimulating osteoblasts, even counteracting glucocorticoid-induced bone loss

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Given that people may need to take medications long term, this raises not only financial and coverage determination questions, but it can affect physical health

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