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This creates a planning problem most researchers don't anticipate until they're staring at leftover solution approaching its expiration

It raises IGF-1 levels (which can drive cell growth), can affect blood sugar regulation, and carries risks of promoting unwanted tissue proliferation

And you may have seen the headlines saying the FDA approved it

Future multicenter studies with longer follow-up periods are needed to validate these findings and better evaluate the long-term benefits and limitations of this treatment approach

When adverse effects occurred, they were typically mild and transient, with the most common being mild to moderate headaches (similar frequency to placebo groups), minor injection site reactions (redness, slight swelling), and gastrointestinal effects at higher oral doses (nausea, diarrhea)