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Although GLP-1RAs exert beneficial effects by delaying gastric emptying, enhancing satiety, and reducing caloric intakemechanisms that predominantly promote FM reductionthey are also associated with a loss of lean mass, particularly in the context of substantial weight loss where muscle preservation is critical for metabolic health [77]

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This slight variation underscores the complexity of cannabis use disorder management in different patient populations and indicates the need for further research

The authors note that the current publication represents an early proof-of-concept analysis and that larger, longer-term studies will be needed to confirm the durability of the reproductive benefits observed