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Molecular mechanisms of increased mucus secretion Secretion of mucins in the airway is continuous, with induced increases in mucin production intracellularly correlating to more concentrated mucin secretion, but secretagogues, such as ATP or histamine, are responsible for the rapid, complete release of granule contents accumulated within mucin-producing cells into the airway lumen (Jaramillo et al., 2018)

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a-c , Difference in abundance in the extracellular cysteinylglycine in medium (a) and relative abundance of intracellular cysteinylglycine (b) and intracellular cysteine (c) for HCC-1806 cells grown in the indicated conditions and time points (n = 3 technical replicates representative from 2 independent experiments, except for c at 24 h, in which n = 2 technical replicates from 2 independent experiments)

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The positive reviews and testimonials shared by these early adopters have further propelled its reputation