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The prevalence substantially decreased over time in four WHO regions including Africa, Americas, South-East Asia, and Western Pacific

Krukowski RA, Bursac Z, Little MA, Klesges RC

Still, some people can experience cravings or side effects like skin irritation from patches

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Stringent Regulations on Combustible Cigarettes: The global regulatory environment surrounding combustible cigarettes has become increasingly restrictive, directly fueling the growth of the smokeless tobacco market