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Mice were treated with pharmacological agents by either intraperitoneal (i.p.) injection or inclusion in the drinking water

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Notwithstanding the strides achieved in genetic manipulation and regenerative technologies, L-DOPA or compounds related to dopamine metabolism such as MAO-B inhibitors remain as the major modes of palliative care for PD patients 39,56

Protein synthesis declines with age, and men lose roughly 12 kg (27%) and women 5 kg (15%) of lean body mass from ages 25 to 70, as measured by potassium-40 counting