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Given the versatility of phenoxyl radicals for covalent tagging of proteins 9 , RNA 10 and DNA 11 and for generating contrast for electron microscopy (EM) 12 , we searched for APEX2-like oxidizing enzymes that do not require toxic H 2 O 2 for labeling

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These studies often employ daily or twice-daily dosing regimens for periods spanning days to weeks, depending on the condition under investigation, such as tissue repair or gastrointestinal healing