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DETOXICATED TOBACCO Article in Scientific American November 11, 1876 A correspondent, referring to our recent article A Cigar Scientifically Dissected, asks whether there is not some method whereby tobacco can be rendered innocuous and yet have its agreeable aroma preserved

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Tobacco-specific nitrosamines (TSNAs) such as N-nitrosonornicotine (NNN) and 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK) have been previously characterized in the vapors of e-cigarettes [35]