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10.1073/pnas.1415174111 Proc Natl Acad Sci U S A

Rare side effects include allergic reactions and changes in blood pressure

It does this by activating endothelial nitric oxide synthase, which is responsible for the production of nitric oxide a potent vasodilator

How it works: Epitalon mimics a natural peptide produced by the pineal gland (called epithalamin) and is thought to work primarily by reactivating telomerase, the enzyme responsible for rebuilding telomeres

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