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Additionally, it was found that the expression of the anti-apoptotic protein Bcl-2 greatly decreased in DMED rats, whilst the levels of the pro-apoptotic proteins Bax and caspase-3 increased

Choudhary, P

Preclinical studies and clinical trials show that ursolic acid in nanoparticle form can have better therapeutic effects without any serious adverse effects [268]

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In cells derived from the blood of individuals with PD, the levels of D1-like receptors are increased in total CD4 + T-cells and nave CD4 + T-cells relative to those of healthy patients, and a decrease in D1 expression was associated with increased motor dysfunction (Kustrimovic et al., 2016)