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This irregularity reflects fluctuating and declining hormone levels

Tirzepatide itself has not been associated with direct nephrotoxicity

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Data were accessed through the secured All of Us Researcher Workbench, a cloud-based platform compliant with federal privacy and security standards ( 2.2 Study design and population We conducted a retrospective nested casecontrol study within a well-defined cohort of adults enrolled in the All of Us Research Program to evaluate the association between GLP-1 RAs exposure and incident SUD diagnoses