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Hormonal role: It produces hormones, most importantly insulin (which lowers blood sugar by moving glucose into cells) and glucagon (which raises blood sugar when it gets too low)

These interesting findings may be also attributed to the weight reduction properties

demonstrated that PPG neurons in the brainstem mediate the reduction of food intake by lorcaserin and that the combination of lorcaserin with GLP-1RA resulted in additive effects on food intake potentially providing a strategy to increase the therapeutic margin of future 5-HT2CR agonists (121)

Endogenous oxidative damage of mtDNA

For the GLP-1 entity overview see GLP-1 Explained