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doi: 10.1080/13510002.2024.2445398 43 ZhangYHuMJiaWLiuGZhangJWangBet al

Aggarwal et al

Nutrition and Metabolism (Lond)

The equivalent residue is a serine or alanine in oxyntomodulin and GLP-1 respectively, contributing to a more stable -helical conformation, while also forming additional interactions at the base of the GLP-1R binding pocket (Figs