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"In vivo nickel allergic contact dermatitis: human model for topical therapeutics." Contact Dermatitis 40.4 (1999): 205-208

May cause temporary fatigue or mild flu-like symptoms in some users

It also disrupts T 3 and T 4 production causing decrease in their levels, increased TSH, oxidative stress, and downregulated antioxidant and thyroid-related genes

If you specifically want the variant with research focused directly on hair follicle applications, choose AHK-Cu Hair Tonic

Microneedle and iontophoresis delivery Advanced delivery systems are being developed to overcome the penetration challenges of topical peptide application