glp 1 discontinuation Treatment among users of GLP-1 receptor agonists and SGLT2 inhibitors in a national population of individuals with type 2 diabetes | Diabetologia REVEAL-1: Sustained post-GLP-1 weight maintenance

However, their consumption is associated with an increased risk of various health consequences

PMID 19820072

In addition, Berberine reduces the release of inflammatory factors such as TNF- and IL-6 by inhibiting the CYP1B1 and NF-B pathways, upregulates miR-204 to target and regulate HIF1/NFATc2, inhibits the crosstalk between oxidative stress and inflammation, and suppresses abnormal cell apoptosis and fibrosis by regulating the Bax/Bcl-2 ratio and TGF-1 expression (Luo et al., 2021

Bonner, R., Albajrami, O., Hudspeth, J

Gene Expression Modulation Influences the expression of genes associated with aging, antioxidant defense, and cellular stress responsepromoting resilience and adaptive capacity at the molecular level