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It is also important to note that depression is highly heterogeneous, and anti-inflammatory agents may not help with overall severity but rather alleviate specific symptoms of depression

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A recent meta-analysis and epidemiological studies have shown that affected individuals can have an increased risk of developing diabetes and CVD [2, 4]

Additionally, a review of 12 studies found that supplementing with berberine led to significant reductions in body weight, body mass index, and belly fat