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If concomitant use is warranted, consider recommending or prescribing an opioid overdose reversal agent (see WARNINGS)

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Sections were blocked with 2.5% normal horse serum (Vector Laboratories) for 1 h, followed by 24 h of incubation with the following rabbit primary antibodies: anti-S100 (1:100, Abcam ab41548), anti-MAOB (1:100, Abcam ab175136, Santacruz sc-515354), and anti-ABAT (1:100, Abcam ab108249)

FoB or MZB cells were seeded in XF Seahorse RPMI medium at 10 6 /well on Seahorse XFe96 culture plates pre-coated with Cell-Tak

Betulin, used as a positive control, has a similar effect on inhibiting SREBP2 maturation as the combined treatment of metformin and simvastatin (Fig