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Cyclooxygenase-2 (COX-2) is a key regulatory molecule that catalyzes the synthesis of arachidonic acid to prostaglandin (PG), which is expressed in large quantities when cells are stimulated by inflammation, accelerating the occurrence of inflammatory storms (105)

The FDA announced it intends to consult the Pharmacy Compounding Advisory Committee (PCAC) before the end of February 2027 regarding potential inclusion of GHK-Cu on the 503A bulks list