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2.3.1 The relationship between ferroptosis and autophagy Appropriate autophagy has evolved into a pro-survival response for cells, but excessive autophagy, especially selective autophagy, and impaired lysosomal activity may promote cellular ferroptosis (92)

There is a theoretical concern that aggressive senolytic clearance could remove this anti-tumor senescence signal, potentially accelerating tumor growth in individuals with pre-malignant cells

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