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Phase 2 dose-ranging trials followed in 20042006, and the pivotal Phase 3 trials (studies LIPO-010-05 and LIPO-010-06) ran from 2006 to 2009 , forming the efficacy basis for the November 2010 FDA approval

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Nat Rev Gastroenterol Hepatol 14(6):343355 Guo L, Kang JS, Park YH, Je BI, Lee YJ, Kang NJ, Park SY, Hwang DY, Choi YW (2020) S-petasin inhibits lipid accumulation in oleic acid-induced HepG2 cells through activation of the AMPK signaling pathway

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