Were targeting a separate satiety circuit the brainstem area postrema pathway that GLP-1 agonists alone dont fully engage
Q: A recent New Yorker article described people who had taken these drugs and reported a side effect of less excitement about life Cummings: There are a lot of hints that the drugs may act in the reward centers of the brain, and those actions may have something to do with why they seem to be associated with lower alcohol and substance abuse and smoking, and other compulsive behaviors like gambling and shopping
--- ## Storage Rules After Reconstitution | Condition | Temperature | Maximum Duration | |-----------|-------------|-----------------| | Refrigerator (ideal) | 3646F (28C) | 28 days from reconstitution | | Room temperature (brief excursion) | Under 77F (25C) | 2 hours maximum | | Frozen | Below 32F | Never discard immediately | **Storage do's:** - Store in the original vial, upright - Keep in the refrigerator door shelf or middle shelf avoid the back where freezing can occur - Protect from light (store in original box or wrap in foil) - Remove from fridge just before drawing your dose
Do not put syringes in regular trash
This Taiwan position statement reviews the literature and provides suggestions regarding the epidemiology, etiology, risk factors, risk stratification, nonpharmacological interventions, and potential drug treatments of MAFLD, focusing on its association with CVD
