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Because it is not a sedative, most people do not experience mid-day drowsiness when taking it

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As such, it is estimated that 60 million Americans consume APAP on a weekly basis ( Acetaminophen hepatotoxicity is characterized by acute liver failure, centrilobular hepatic necrosis, renal tubular necrosis and hypoglycemic coma (Lancaster et al., 2015), an outcome that can be more frequent with the use of APAP at doses above the therapeutic range

Room Temperature Storage : If needed, an unopened pen may be stored at room temperature (up to 86F or 30C) for up to 21 days before use