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ML226 treatment resulted in HIF-1 stabilization, upregulation of HIF-1 target genes ( CAIX and VEGF ), and activation of a HIF-1 fluorescent reporter (HRE-GFP ODD ) in HeLa cells, similar to treatment with cell-permeable (DM-2OG

CONCLUSION AND PERSPECTIVES During the purine catabolism, there are three major purine bases and their corresponding ribonucleosides, which consist of adenine/adenosine, G/Gr, and Hx/inosine ( Figure 2 )

The role of macrophages and apoptotic cell clearance in the maintenance of liver tolerance (Doctoral dissertation, Staats-und Universittsbibliothek Hamburg Carl von Ossietzky)

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