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Alterations in gut microbiota composition depend on many factors, such as host genetics and health status, antibiotic use as well as various environmental factors including (ketogenic) diet, sleep, and exercise [295,296,297,298]

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Other indicators for assessing proper fruit maturity include the volume of liquid (coconut water) inside the fruit, which can be detected by the sloshing sound when shaking a ripe fruit, the brown husk color (as opposed to gray), and a uniformly brown soft eye without signs of moisture or a protruding embryo (Foale 2003)

340 Tri-Agonist for GLP-1R, GIPR and GCGR Recently, a triple agonist for GLP-1R, GIPR and GCGR was developed and tested on diet-induced obese mice