The dual activation of HACD44 and GSHNrf2 signaling pathways establishes a finely balanced biochemical microenvironment that supports cell proliferation, angiogenesis, and extracellular matrix maturation while preventing oxidative and inflammatory overactivation
1% of collagen is lost every year after the age of 20
doi:10.1001/jama.2023.24945 Caro, R., Samsel, D., & Savel, P
In addition to the neuropharmacological effects of GIPR antagonism, we also demonstrate that CNS GIPR KO prevents body weight gain under HFD challenge, supporting the role of CNS GIPR as a primary driver of body weight differences seen in the whole-body GIPR KO mouse 41
Dairy chemistry: a practical handbook for dairy chemists and others having control of dairies