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FDA approval of Foundayo orforglipron, a once-daily oral GLP-1 receptor agonist for adults with obesity or overweight with weight-related medical problems, expanding competition in non-injectable obesity drugs

Consistently, after 10 weeks on a drug that lowers rather than raises free radical levels, normal mice ended up with 31% fewer Bacteroidales, and more than twice as many Clostridia, as before (Yardeni et al., 2019)

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Tilak Shah In 2022, the American Society of Anesthesiologists issued a consensus statement that patients on GLP-1 agonists should hold a dose of the medication based on anecdotal reports, Shah told Healio

Christina Nguyen put it plainly: if Foundayo is competitive on price with oral Wegovy, "most likely everyone will go with the orforglipron." Novo pushed back on that framing