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RP-UPLC separation was performed on the Acquity UPLC system (Waters, column: BEH C18 1.7 m, 2.1 50 mm)

Proc R Soc Lond I (1901) 69:352353

Nanoparticle-based delivery systems have emerged as promising solutions, offering enhanced brain delivery, reduced systemic toxicity, and sustained release of neuroprotective agents, including phytochemicals and small molecules [56,57,58]

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