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Zepbound (tirzepatide) activates GLP-1 and GIP receptors in the brain, which can reduce saliva production and cause dry mouth in up to 40% of users during the first few weeks of treatment

Semaglutide: The Single GLP-1 Agonist Semaglutide is a 31-residue GLP-1 analogue engineered to survive plasma long enough to be useful