Prior authorization denial rates for GLP-1 obesity prescriptions have been high, and industry reporting through 2024 put them well above half of requests in some plans
The initial dose, often 2.5mg once weekly, is primarily designed to help your body gradually adjust to the medication, minimizing potential side effects, rather than immediately triggering dramatic changes
[1] [2] It works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite
Heffron and his team, however, had begun their study a year earlier
Patients with diabetes are educated on how to integrate a balanced, calorie-restricted diet and at least moderate physical activity in their routine