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and Sumin Son, B.A., and Matthew Lee, B.S., medical students

After this, cigarette ads stopped featuring doctors because this was no longer a convincing tactic

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Systems toxicology analyses detected biological effects of nicotine exposure, which included up-regulation of the xenobiotic-metabolizing enzymes CYP1A1 and FMO3 in the lung and metabolic effects, likely interlinked with a generalized stress response to nicotine present in the exposure aerosols [34]

Some brands even offered "cigarettes" you could blow through, sending a puff of powder out the end