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doi: 10.1038/s41576-019-0151-1 107 TanXSunLChenJChenZJ

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Additionally, it needs to be considered that PBMC are a heterogenous population with diverse cell types

CDC (2023) General Best Practice Guidelines for Immunization: Vaccine Administration Related research, protocols, and guides Explore the available research context, protocol variants or comparisons, and practical guides

Light exposure controls the secretion of melatonin, and the sun going down (lack of light) allows for the rise of melatonin at night