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Discovery and development of MEDI7247, a novel pyrrolobenzodiazepine (PBD)-based antibody drug conjugate targeting ASCT2, for treating hematological cancers

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The accumulation of ROS leading to lipid peroxidation is considered the principal mechanism underlying sarcolysis in muscular dystrophy

As of March 2024, an ongoing study at Howard University in the United States plans to recruit 100 people with mild-to-moderate ulcerative colitis to further assess the efficacy of saffron supplementation in this context (Ashktorab 2021)