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Moreover, heart rate was increased up to 120 min following exposure to ENDS with nicotine, even in frequent young users of combustible tobacco products [24]

Securities and Exchange Commission which attempt to advise interested parties of the risks and factors that may affect our business, financial condition, results of operation and cash flows

However, there is some evidence that synthetic nicotine is more readily absorbed by the body than tobacco-based nicotine and therefore could be more addictive

however, longitudinal investigations are required to further validate this relationship