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Thiel, A., Weishaupt, A.-K., Nicolai, M

2 Molecular mechanisms by which lipid peroxidation affects muscle atrophy Free radicals, particularly reactive oxygen species (ROS) and reactive nitrogen species (RNS), are the primary inducers of lipid peroxidation

On the other hand, PSI photoinhibition results from the over-reduction of PSI relative to the conventional stromal acceptors and the subsequent reduction of O 2 as an alternative electron acceptor

This movement is caused by cellular swelling and a relative narrowing of extracellular gaps, which in turn generate slow-conducting waves of depolarization in multiple neurons and glial cells, resulting in the temporary inhibition of synaptic activity ( 2+ overload induces a transient oxidative stress in the organism and promotes the generation of ROS, which activate injurious signaling through transient receptor potential subtype anchor protein 1 channels ( 2+ lead to the opening of neuronal pannexin 1 channels to open and activate cystatinase 1, followed by the release of high mobility group box-1 protein and the activation of nuclear factor kappa-B signaling pathway in astrocytes (Figure 1B)

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