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It has a role as a flour treatment agent, a human metabolite and an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor

[1] Clinical efficacy depends on consistent administration combined with lifestyle modifications including reduced-calorie diet and increased physical activity

Beyond established pharmacological mechanisms such as improved glucose-dependent insulin secretion, delayed gastric emptying, and appetite modulation, growing evidence indicates that the intestinal microbial ecosystem may contribute to interindividual differences in treatment outcomes

The more overall weight loss, the more muscle mass loss, says Dr

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