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b , Immunoblot of SLC25A39, SLC25A12 and CS in HeLa cells treated with the indicated doses of BSO for 24 h

"It also restored mobility to osteoarthritic mice and significantly reduced their pain." As a proof of principle that this might also work in humans, the researchers transferred human tissue into mice that were bred to not reject the tissue, and were able to show that human skeletal stem cells could be steered toward bone development but stopped at the cartilage stage

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FASEB J 24:25332545 Jones DP (2006) Redefining oxidative stress