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Sugar (sucrose) is a disaccharide composed of glucose and fructose

Insulin resistance in obesity as the underlying cause for the metabolic syndrome

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To capture cancer-specific metabolic alterations on a genome scale, and to examine how these alterations could be exploited to derive novel melanoma treatment regimens, we have reconstructed over 10,000 metabolic models, and computationally identified 54 putative gene targets and 12 drug candidates for melanoma treatment