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Mechanistic insights support preventive strategies such as genotype-guided dosing, structured liver function monitoring, and adjunctive therapies targeting oxidative stress, mitochondrial stabilization, or bile acid homeostasis

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Pretreatment without peptides was used as a negative control, while treatment with an anti-aging peptide, acetyl hexapeptide-8 (Wrinklend), was taken as a positive control

Also, an analysis by meta-analysis of controlled trials has shown that low-carb diets have a significant impact on BMI, HOMA-IR (insulin resistance), and cholesterol content, especially when interventions last more than four weeks [76]