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Insulin Secretion: In response to high blood sugar, they help increase the bodys insulin production, which lowers blood glucose levels

Targeting both receptors simultaneously, as with tirzepatide, leverages these complementary effects, enhancing insulin secretion [3], reducing appetite, improving insulin sensitivity, and supporting weight loss more effectively than single receptor agonists

The sensation may be most pronounced following meals or during dose escalation periods, and some patients find that eating smaller, more frequent meals helps minimize this discomfort

doi: 10.1056/NEJMoa1411892 [DOI] [PubMed] [Google Scholar] 23

Yes, but only through providers that have integrated Afterpay into their checkout system