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Causes of deficiency may include a diet low in cysteine and other essential nutrients, increased pollution, excessive alcohol consumption, and certain medical conditions

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First, as with other studies using electronic health databases, the analysis of the TriNetX database relies heavily on diagnosis codes, which may introduce both misclassification bias due to coding errors and ascertainment bias from the underrepresentation of mild cases

That said, heres how we generally see diminishing returns being calculated in MMM: 2 of the most common curves S-curve and concave show that the efficiency of marketing efforts declines exponentially

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