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doi: 10.3389/fpls.2025.1645191 Received 11 June 2025 Accepted 27 October 2025 Published 21 November 2025 Volume 16 - 2025 Edited by Linda De Bont, Universit de Lorraine, France Reviewed by Kollipara P

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Abstract This large community-based cohort study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically Liraglutide and Semaglutide, on the risk of developing psychiatric conditions such as depression, anxiety, and suicidal behaviors in patients with obesity