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By inhibiting H3 histone lactylation (H3K9la and H3K56la), demethylzeylasteral decreased the tumorigenesis driven by liver cancer stem cells (LCSCs) both in vivo and in vitro
However, the promotion or inhibition of HO-1 for ferroptosis has obtained contradictory results, so the relationship between them needs to be further explored [41, 42]
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