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Although ARA 290 has a short serum half-life of a few minutes (11), the peak plasma concentrations attained after the administration of 2 mg intravenously in normal human volunteers in pharmacokinetic studies reached ~50 ng/mL, exceeding the minimum effective peak concentration of ~1 ng/mL (26)

The peptide appears to interact with the dopaminergic and serotonergic systems, which may contribute to its effects on pain perception and mood

Specific cells in the stomach lining, called parietal cells, secrete two substances that are important to B12 absorption

That said, a PCAC vote is advisory, not binding, meaning real-world access for patients hasn't changed

One thing it cant do is make vitamin B12