doi: 10.1016/j.jns.2012.01.026
Visible skin brightening typically appears at 5-8 weeks with continued improvement over 3-6 months
Gong et al., 2016) have underscored the potential of TMP as an innovative therapeutic option in CI-AKI prevention by suppressing the p38 MAPK and FoxO1 pathways, additionally protecting renal tubular cells against arsenite-induced nephrotoxicity by averting mitochondrial dysfunction and regulating autophagy
Among patients with identifiable aetiological factors, the use of targeted interventions, including antibiotics, is associated with a significant reduction in the frequency of diarrhoea 172,173
A recent regulatory example, accepted by the US EPA, of a non-animal risk assessment for the fungicide chlorothalonil in an occupational scenario combined in vitro PoDs from MucilAir readouts (i.e., TEER, lactate dehydrogenase leakage and resazurin metabolism analyses) with dosimetry information obtained from a computational fluid-particle dynamics (CFPD) model (Corley et al., 2021