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50 Activated AMPK then promotes glucose uptake through the translocation of GLUT4, suppresses gluconeogenesis by inhibiting G6Pase and PEPCK, and improves lipid metabolism by inhibiting fatty acid synthesis and promoting its oxidation

You heard of Tal-corset ( ), right? asked Professor Hyun Mee Kim at Yonsei University

While the nephroprotective effects of SGLT2i were initially derived from secondary endpoints of CV outcome trials (CVOTs), direct confirmation came from dedicated kidney focused trials: CREDENCE (Perkovic et al NEJM 2019| NephJC Summary), DAPA-CKD (Heerspink et al NEJM 2020| NephJC Summary) and finally EMPAKIDNEY (Herrington et al NEJM 2023| NephJC Summary)

Vitamin E therapy on aminotransferase levels in NAFLD/NASH patients

Be cautious of products making exaggerated health claims, as these are not permitted under UK regulations