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El KhoudarySRVenugopalVMansonJEBrooksMMSantoroNBlackDMet al

This review provides a comprehensive overview of recent advances in the rational design, chemical synthesis, and biological evaluation of promising XO inhibitors for the treatment of hyperuricemia and gout

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Potential solutions to this problem may lie in using natural products and medicinal plants, which have shown promise in enhancing antioxidant defenses and controlling diabetes

Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation