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Despite the FDA highlighting safety issues with compounded GLP-1RAs, this type of medications use has skyrocketed
Aziz MT, Mostafa T, Atta H, Rashed L, Marzouk SA, Obaia EM, et al
Nutrire 50 , 71 (2025)
This is the same physiologic process seen when someone stops lifting weights: muscle size decreases because the stimulus is gonenot because muscle is being destroyed. Common Misconception: GLP-1 Drugs Burn Muscle Reality: Muscle loss during GLP-1associated weight loss is driven by reduced mechanical load and insufficient protein/calories , not by a toxic or catabolic drug effect. When Lean-Mass Loss Becomes True Muscle Wasting True muscle wasting is uncommon with GLP-1 therapy and is usually related to undernutrition , not the medication itself
In-focus single-cell images were acquired with a 60 magnification and a low-speed flow rate using the INSPIRE software (EMD Millipore)
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